中国医科大学：《诊断学》课程教学课件（PPT讲稿）Blood gas analysis

Blood gas analysis and acid-basic disorder Department of internal medicine Chen Yu

Blood gas analysis and acid-basic disorder Department of internal medicine Chen Yu

Blood Gas Analysis Arterial blood >Sea level (101.3kPa,760mmHg) Quiet Anti-coagulate blood Inspire air (Whether O2 supply)

Blood Gas Analysis ➢ Arterial blood ➢ Sea level (101.3kPa, 760mmHg) ➢ Quiet ➢ Anti-coagulate blood ➢ Inspire air (Whether O2 supply)

Clinical Significance To evaluate respiratory failure type I or type II To evaluate acid-basic disorder

Clinical Significance ➢To evaluate respiratory failure type Ⅰ or type Ⅱ ➢To evaluate acid-basic disorder

How to evaluate respiratory failure? PaO2: Arterial blood oxygenic partial pressure. Normal:95-100mmHg (12.6-13.3kPa) Estimate formula of age: Pa02=100mmHg-(age×0.33)士5mmHg

How to evaluate respiratory failure? PaO2 : Arterial blood oxygenic partial pressure. Normal: 95-100mmHg (12.6-13.3kPa) Estimate formula of age: PaO2=100mmHg-(age×0.33) ±5mmHg

Hypoxia Mild:80-60mmHg Mediate:60-40mmHg Severe:<40mmHg

Hypoxia ➢Mild: 80-60mmHg ➢Mediate: 60-40mmHg ➢Severe: <40mmHg

Respiratory Failure PaO2<60mmHg-respiratory failure Notice:sea level,quiet,inspire air rule off other causes heart disease)

Respiratory Failure PaO2<60mmHg respiratory failure Notice: sea level, quiet, inspire air rule off other causes ( heart disease)

Classification of Respiratory Failure PaCO,:The carbon dioxide partial pressure of arterial blood Normal:35-45mmHg (4.7-6.0kPa) mean:40mmHg

Classification of Respiratory Failure PaCO2 : The carbon dioxide partial pressure of arterial blood Normal: 35-45mmHg (4.7-6.0kPa) mean: 40mmHg

Classification of Respiratory Failure Type I Type II PaO2 (mmHg) 50

Classification of Respiratory Failure Type Ⅰ TypeⅡ PaO2 (mmHg) 50

Other Parameters Sa02:Saturation of arterial blood oxygen Normal::0.95-0.98 Significance:a parameter to evaluate hypoxia,but not sensitive ODC Dissociation curve of oxygenated hemoglobin):“S”shape

Other Parameters SaO2: Saturation of arterial blood oxygen Normal: 0.95-0.98 Significance: a parameter to evaluate hypoxia, but not sensitive ODC ( Dissociation curve of oxygenated hemoglobin): “S” shape

Sa02% 100 259% 259% 80 60 40 3.56.9 P02 0 2.7 5.3 8.0 10.6 13.316.0 kPa Oxygen dissociation curve

SaO2% PO2 Oxygen dissociation curve