《材料导论》课程教学资源（文献资料）诺贝尔奖获得者 nobel

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2002 ■John B.Fenn ■Research area: Methods,mechanisms and applications of Electrospray Ionization Mass Spectrometry. PDF文件使用"pdfFactory Pro”试用版本创建ww,fineprint..com.cn

2002 n John B. Fenn n Research area： Methods, mechanisms and applications of Electrospray Ionization Mass Spectrometry. PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn

John Fenn's 60-year career in chemistry includes constant intellectual movement,with contributions that changed how chemistry was done marking the way.In 2002,the Nobel Prize awards committee honored Fenn for his invention of a pioneering technique that allows researchers to determine the mass of large biological molecules,such as proteins,peptides and DNA.Later, he was elected to the National Academy of Scienceis comprised of nearly 2,000 members and Fenn is its only Virginia chemist. John's career has included time in industry (Monsanto (1940- 43),Sharples Chemicals (1943-45)and Experiment Inc.(1945-52) and academe (Princeton University (1952-66),Yale University (1967-87,then becoming professor emeritus)and VCU(1994- present).Many of his projects have drawn interest and support from such government agencies as the Office of Naval Research, National Science Foundation and National Institutes of Health. He has served as a visiting professor at Trento University in Italy, the University of Tokyo,the Indian Institute of Science at Bangalore and the Chinese Academy of Science in Beijing and as a distinguished lecturer at several other institutions.Author of one book and more than 100 papers,he is sole or co-inventor on 19 patents. PDF文件使用"pdfFactory Pro”试用版本创建ww,fineprint.com.cn

n John Fenn's 60-year career in chemistry includes constant intellectual movement, with contributions that changed how chemistry was done marking the way. In 2002, the Nobel Prize awards committee honored Fenn for his invention of a pioneering technique that allows researchers to determine the mass of large biological molecules, such as proteins, peptides and DNA. Later, he was elected to the National Academy of Scienceis comprised of nearly 2,000 members and Fenn is its only Virginia chemist. John’ s career has included time in industry (Monsanto (1940- 43), Sharples Chemicals (1943-45) and Experiment Inc. (1945-52) and academe (Princeton University (1952-66), Yale University (1967-87, then becoming professor emeritus) and VCU (1994- present). Many of his projects have drawn interest and support from such government agencies as the Office of Naval Research, National Science Foundation and National Institutes of Health. He has served as a visiting professor at Trento University in Italy, the University of Tokyo, the Indian Institute of Science at Bangalore and the Chinese Academy of Science in Beijing and as a distinguished lecturer at several other institutions. Author of one book and more than 100 papers, he is sole or co-inventor on 19 patents. PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn

■contact ■ibfenn@xcm.edu mailing address: VCU Department of Chemistry 1001 W.Main St. P.O.B0x842006 Richmond VA 23284-2006 Phone:804.828.1298 Fax:804.828.8599 PDF文件使用"pdfFactory Pro”试用版本创建mw,fineprint..com,cn

n contact n jbfenn@vcu.edu mailing address: VCU Department of Chemistry 1001 W. Main St. P.O. Box 842006 Richmond VA 23284-2006 Phone: 804.828.1298 Fax: 804.828.8599 PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn

J.B.Fenn,M.Mann,C.K.Meng,S.F.Wong and C.M. Whitehouse,Science 246,64 (1989) 用 "Electrospray Mass Spectrometry of Poly(ethylene glycols)with Molecular Weights up to Five Million,"T.Nohmi and J.B.Fenn (1992) ■ "Three-dimensional Deconvolution of Multiply Charged Spectra,"M.J Labowsky,C.M.Whitehouse and J.B.Fenn, Rapid Communications in Mass Spectrometry,7,71(1993) "Ion Formation from Charged Droplets:Roles of Geometry, Energy and Time,"J.B.Fenn,J.Am.Soc.Mass Spectrom.4, 5241993) PDF文件使用"pdfFactory Pro”试用版本创建wm,fineprint.com,cn

n J. B. Fenn, M. Mann, C. K. Meng, S. F. Wong and C. M. Whitehouse, Science 246, 64 (1989) n "Electrospray Mass Spectrometry of Poly(ethylene glycols) with Molecular Weights up to Five Million, " T. Nohmi and J. B. Fenn (1992) n "Three-dimensional Deconvolution of Multiply Charged Spectra, " M. J Labowsky, C. M. Whitehouse and J. B. Fenn, Rapid Communications in Mass Spectrometry, 7, 71 (1993) n "Ion Formation from Charged Droplets: Roles of Geometry, Energy and Time, " J. B. Fenn, J. Am. Soc. Mass Spectrom. 4, 524 (1993) PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn

2003 Roderick MacKinnon and Peter Agre PDF文件使用"pdfFactory Pro”试用版本创建mw,fineprint..com,cn

2003 Roderick MacKinnon and Peter Agre PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn

0.5 min 1.5 min 2.5 min 3.5min Cell with Cell without quaporin Water channel Cell membran Cell membrane 6 3 PDF文件使用"pdfFactory Pro”试用版本创建www,fineprint.com.cn

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lon filte Cell membrane Cell membrane Gate PDF文件使用"pdfFactory Pro”试用版本创建ww,fineprint..con.cn

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Roderick MacKinnon Howard Hughes Medical InstituteLaboratory of Molecular Neurobiology and BiophysicsRockefeller University1230 York Avenue,New York,New York 10021USA E-mail:mackinn@rockefeller.edu US citizen. PDF文件使用"pdfFactory Pro'”试用版本创建wm,fineprint..co.cn

Roderick MacKinnon n Howard Hughes Medical InstituteLaboratory of Molecular Neurobiology and BiophysicsRockefeller University1230 York Avenue, New York,New York 10021USA E-mail: mackinn@rockefeller.edu US citizen. n PDF 文件使用 "pdfFactory Pro" 试用版本创建 www.fineprint.com.cn

Roderick MacKinnon Born 1956(47 years).Grew up in Burlington outside Boston, USA.B.A.at Brandeis University,Boston,1978.M.D.at Tufts Medical School in Boston,1982.Since 1996,Professor of Molecular Neurobiology and Biophysics at The Rockefeller University in New York.Roderick MacKinnon studies the principles of electricity in biology through analysis of ion channel structure and function.Ion channels catalyze the diffusion of inorganic ions down their electrochemical gradients across cell membranes.Because the ionic movements are passive,ion channels would seem to be extraordinarily simple physical systems,and yet they are responsible for all electrical signaling in biology.Among their many functions,ion channels control the pace of the heart,regulate the secretion of hormones into the bloodstream,and generate the electrical impulses underlying information transfer in the nervous system.My research is aimed at understanding the physical and chemical principles underlying ion channel function. PDF文件使用"pdfFactory Pro”试用版本创建iw,fineprint.com.c如

Roderick MacKinnon n Born 1956 (47 years). Grew up in Burlington outside Boston, USA. B.A. at Brandeis University, Boston, 1978. M.D. at Tufts Medical School in Boston, 1982. Since 1996, Professor of Molecular Neurobiology and Biophysics at The Rockefeller University in New York. Roderick MacKinnon studies the principles of electricity in biology through analysis of ion channel structure and function.Ion channels catalyze the diffusion of inorganic ions down their electrochemical gradients across cell membranes. Because the ionic movements are passive, ion channels would seem to be extraordinarily simple physical systems, and yet they are responsible for all electrical signaling in biology. Among their many functions, ion channels control the pace of the heart, regulate the secretion of hormones into the bloodstream, and generate the electrical impulses underlying information transfer in the nervous system. My research is aimed at understanding the physical and chemical principles underlying ion channel function. PDF 文件使用 "pdfFactory Pro" 试用版本创建 ÿwww.fineprint.com.cn