北京大学：《病理学》课程PPT教学课件（讲稿）神经系统疾病 Diseases of Nervous System

83 Infections 病因诊断技术 Electron microscope Immunohistochemistry免疫组织化学 Hybridization in situ原位杂交 Cultivation培养 · Immunoassay兔疫检测 ·PCR 多聚酶链反应

§3 Infections 病因诊断技术 •Electron microscope • Immunohistochemistry 免疫组织化学 • Hybridization in situ 原位杂交 •Cultivation 培养 • Immunoassay 免疫检测 • PCR 多聚酶链反应

神经系统感弟性疾病 I. Acute pyogenic meningitis 急性化性脑膜炎 病因青少年: meningococcus脑膜炎双球菌 发病机制 局部炎症 病人 飞沫 带菌者 呼吸道呼吸道血 (脑膜 · Epidemic meningitis流行性脑膜炎(流脑)

神经系统感染性疾病 I. Acute pyogenic meningitis 急性化脓性脑膜炎 病因 青少年: meningococcus 脑膜炎双球菌 发病机制 病人 带菌者 飞沫 呼吸道 上呼吸道 脑膜 血 • Epidemic meningitis 流行性脑膜炎（流脑） 局部炎症

Acute pyogenic meningitis 病变 Pyogenic inflammation of leptomeninges 软脑膜蛛网膜的化脓性炎 肉眼:脑脊膜血管高度扩张充血 蛛网膜下腔充满脓性渗出物 光镜:嗜中性白细胞为主的炎细胞浸润

病变 Pyogenic inflammation of leptomeninges 软脑膜蛛网膜的化脓性炎 肉眼：脑脊膜血管高度扩张充血， 蛛网膜下腔充满脓性渗出物 光镜：嗜中性白细胞为主的炎细胞浸润 Acute pyogenic meningitis

化脓性脑膜炎 Here is another example of an acute meningitis from bacterial infection. The cerebrospinal fluid (csfiin such cases typically has a low glucose, high protein, and many PMns. a gram stain should be done to dentify organisms

Here is another example of an acute meningitis from bacterial infection. The cerebrospinal fluid (CSF) in such cases typically has a low glucose, high protein, and many PMN's. A gram stain should be done to identify organisms

a0命 3 a gram stain reveals gram negative diplococci within a neutrophil, typical for Neisseria meningitidis Gram stain and culture can be performed on cerebrospinal fluid obtained via lumbar puncture. A variety of bacteria can cause meningitis, but several are more common, and have an incidence more frequent at certain ages:

a gram stain reveals gram negative diplococci within a neutrophil, typical for Neisseria meningitidis. Gram stain and culture can be performed on cerebrospinal fluid obtained via lumbar puncture. A variety of bacteria can cause meningitis, but several are more common, and have an incidence more frequent at certain ages: 191

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Acute pyogenic meningitis 临床病理联系 颅内压增高 脑膜刺激症状 脑脊液变化 结局和后遗症 脑膜粘连 颅神经受损

临床病理联系 颅内压增高 脑膜刺激症状 脑脊液变化 结局和后遗症 脑膜粘连 颅神经受损 Acute pyogenic meningitis