上海交通大学：《药物化学》课程教学资源（课后题库）Chapter 12 Antiviral

1.Describe the main differences between each of the following: (a)human immunodeficiency virus protease inhibitors and HIV integrase inhibitors; (b)nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors and (c)hemagglutinin and neuraminidase. 2.What are neuraminidase inhibitor?How do they act? 3.Suggest reasons for resistance to antiviral agents. 4.Outline,using suitable examples,the general modes of action of antiviral drugs

1. Describe the main differences between each of the following: (a) human immunodeficiency virus protease inhibitors and HIV integrase inhibitors; (b) nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors and (c) hemagglutinin and neuraminidase. 2. What are neuraminidase inhibitor? How do they act? 3. Suggest reasons for resistance to antiviral agents. 4. Outline, using suitable examples, the general modes of action of antiviral drugs